CDC's Role in Preventing Extensively Drug-Resistant
Tuberculosis (XDR TB)
||CDC's Role in Preventing Extensively
Drug-Resistant Tuberculosis (XDR TB)
Posted: April 2007
The Centers for Disease Control and Prevention (CDC) is collaborating
with other federal agencies and international partners to raise
awareness and enhance strategies for TB prevention worldwide by
Strengthening TB services for people living with HIV/AIDS
The President’s Emergency Plan for AIDS Relief (PEPFAR),
through funding and technical support, helps host countries strengthen
laboratory infrastructure, provide staff training, and screen
patients who are HIV-infected for TB. Host countries are working
to improve patient management, drug-resistance surveillance, and
monitoring and evaluation efforts.
Assembling outbreak response teams
Teams of subject matter experts from CDC are prepared to be rapidly
deployed to help host country governments and the World Health
Organization (WHO) when outbreaks occur or other needs are identified.
Improving access to TB drugs
As a member of the Green Light Committee and through support
of the Global Drug Facility, CDC is helping to increase access
to quality-assured, lower-cost second-line drugs to treat drug-resistant
Developing international TB testing standards
These recommendations are being designed to ensure more accurate
and rapid detection and treatment of drug-resistant TB. They will
include standards for second-line drug susceptibility testing,
new anti-TB drug regimens, and better diagnostic testing.
Building capacity of health care providers
By providing technical support and training, CDC helps to build
the capacity of frontline health care providers to diagnose and
ensure completion of treatment, which aids in preventing drug
Reconvening the Federal TB Task Force
This task force was originally created to respond to the emergence
of multidrug-resistant tuberculosis (MDR TB) in the U.S. in the
1990s. Today, the Federal TB Task Force is developing an action
plan to combat XDR TB.
Providing technical assistance to expand program capacity
CDC and partners are working directly with host countries to
implement improved infection control measures, rapid case detection,
effective treatment, and drug resistance surveillance.
Supporting TB communication and education efforts
Information on XDR TB is being disseminated regularly and widely.
This information is regularly updated on the CDC and partner websites,
as well as being presented at national and international conferences
Note: In addition to CDC, U.S. government partners include the
President’s Emergency Plan for AIDS Relief (PEPFAR), United
States Agency for International Development (USAID) Tuberculosis
Control Assistance Program (TBCAP), and the National Institutes
of Health (NIH). Other domestic partners include the National Tuberculosis
Controllers Association (NTCA) and local and state TB programs.
International partners include the World Health Organization (WHO),
the Stop TB Partnership, the International Union Against Tuberculosis
and Lung Disease (IUATLD), national TB programs, and ministries
Extensively Drug-resistant Tuberculosis (XDR TB)
Extensively Drug-Resistant Tuberculosis - United States, 1993—2006
Organization. Extensively drug-resistant tuberculosis (XDR TB) website