Articles

Pediatric Tuberculosis - Pediatrics in Review

Andrea T. Cruz, MD Jeffrey R. Starke, MD - Baylor College of Medicine
Close up to a girls eye (side view)

Tuberculosis (TB) is an ancient disease, with evidence of skeletal TB found in mummies in both the Old and New World. The causative agent is Mycobacterium tuberculosis, a fastidious, aerobic, acid-fast bacillus. In the wake of human immunodeficiency virus (HIV) infection, the number of children and adults afflicted with TB has escalated tremendously worldwide in the past 25 years.

Eval TB Diagnostics in Child #1

J Infect Dis.(2012) 205 (suppl 2): S209-S215
Chest x-ray

Confirming the diagnosis of childhood tuberculosis is a major challenge. However, research on childhood 35 tuberculosis as it relates to better diagnostics is often neglected because of technical difficulties, such as the slow growth in culture, the difficulty of obtaining specimens, and the diverse and relatively nonspecific clinical presentation of tuberculosis in this age group.

Eval TB Diagnostics in Child #2

J Infect Dis.(2012) 205(suppl 2): S209-S215
Chest x-ray

Confirming the diagnosis of childhood tuberculosis is a major challenge. However, research on childhood 35 tuberculosis as it relates to better diagnostics is often neglected because of technical difficulties, such as the slow growth in culture, the difficulty of obtaining specimens, and the diverse and relatively nonspecific clinical presentation of tuberculosis in this age group.

Addressing Childhood Tuberculosis: Shedding Light on a Hidden Epidemic

Susan A. Maloney, MD, MPH, Global TB Coordinator, CDC Center for Global Health
Child reaching up to grab a leaf from a tree.

Today is World TB Day, and while we have made great progress to control and cure TB, we must recognize that there is still more that needs to be done. TB remains an urgent public health problem in many parts of the world, often affecting the most vulnerable. In 2012, a total of 8.6 million people became ill with TB and 1.3 million died from the disease globally.

Roadmap for Childhood Tuberculosis

World Health Organization
Portriat of a girl smiling

The goal of reaching zero tuberculosis (TB) deaths among children worldwide is within our grasp. Achieving this requires sustained advocacy, greater commitment, mobilization of increased resources and a joint effort by all stakeholders involved in providing health care for children and in TB control. This roadmap indicates key actions and the enhanced investment urgently needed to tackle childhood TB.

A Research Agenda For Childhood Tuberculosis

World Health Organization
Baby looking up to mother while they both smile

Childhood TB is a neglected aspect of the TB epidemic, despite constituting 20% or more of the TB case-load in many countries with high TB incidence. This "orphan disease" exists in the shadow of adult TB and is a significant child health problem, but is neglected because it is usually smear-negative and is thus considered to make a relatively minor contribution to the spread of TB.

Questions and answers about TB

Centers for Disease Control and Prevention
Picture of a care taker talking to a parent

Questions and Answers About Tuberculosis ( TB) was written to provide information on the diagnosis and treatment of TB infection and TB disease for persons who do not have a medical background. Key audiences for this booklet are persons with or at risk for TB; persons who provide services for those at high risk for TB such as correctional officers, homeless shelter workers, emergency responders.

Burden of childhood tuberculosis in 22 high-burden countries

Peter J Dodd, Elizabeth Gardiner, Renia Coghlan, James A Seddon
Graphic of an algorithm

Tuberculosis is largely a disease of poverty, and therefore children with the disease frequently live in poor communities with few health services